The science

Peer-reviewed. Not just trending.

Every protocol we offer is rooted in published clinical evidence — the kind that gets cited in NEJM and JAMA. Below are the studies we actually read.

Board-certified clinicians on staff

503A

State-licensed compounding pharmacies

100%

Third-party lab tested, batch-level

Always

Sourced against current NEJM / JAMA literature

Protocols, by the evidence

The GLP-1 protocols, and the studies behind them.

STEP 1, STEP 3

Semaglutide (active ingredient) — the trial record

In STEP 1, the FDA-approved semaglutide product at 2.4 mg weekly produced ~15% placebo-adjusted weight loss over 68 weeks in non-diabetic adults with obesity. These trials studied the FDA-approved medication — not compounded formulations. Your provider determines your starting dose and titration schedule based on your assessment and response.

→ NEJM 2021 · Wilding et al., Semaglutide in Adults with Overweight or Obesity
→ JAMA 2021 · Rubino et al., STEP 4 — Effect of continued vs withdrawn treatment

SURMOUNT-1, SURMOUNT-2

Tirzepatide (active ingredient) — the trial record

In SURMOUNT-1, the FDA-approved tirzepatide product — a dual GIP + GLP-1 agonist — produced ~21% mean weight reduction at 72 weeks. These trials studied the FDA-approved medication — not compounded formulations. Dosing is individualized by your provider.

→ NEJM 2022 · Jastreboff et al., Tirzepatide Once Weekly for Obesity

Medical advisory

Chaired by physicians who publish — not just prescribe.

Our medical advisory board reviews protocol updates monthly. When new evidence changes the picture — like the recent NEJM tirzepatide data — the protocols shift, and you'll hear about it from your care team before you'd hear about it anywhere else.

Peer-reviewed. Not just trending.

The GLP-1 protocols, and the studies behind them.

Semaglutide (active ingredient) — the trial record

Tirzepatide (active ingredient) — the trial record

Chaired by physicians who publish — not just prescribe.

Titration & the plateau

What compounded means